MS CD180 BV650 RP/14 50UG
货号：
740558 基本售价：
7000.0 元 规格：
50ug
产品信息
概述| 货号 | 740558 |
| 描述 | The RP/14 monoclonal antibody specifically binds to CD180, the "radioprotective" 105 kDa (RP105) antigen expressed on mature B lymphocytes. Like other members of the Toll-like Receptor (TLR) family, the extracellular region of CD180 contains tandem repeats of a leucine-rich motif flanked by regions containing conserved cysteines. These characteristic structural components of TLR may mediate protein-protein interactions and regulation of signal transduction involved in innate immune responses. Furthermore, CD180 associates with the secretory protein MD-1 on the cell surface. Cross-linking of cell-surface CD180 with the RP/14 antibody induces activation signals in B lymphocytes. Despite the expression of CD180 on lymphocytes of all strains tested (BALB/c, BALB/c. xid , C3H, C57BL/6, CBA/N, and 129/Sv), some strains (BALB/c. xid , C57BL/6. xid , CBA/N, 129/Sv, and 129/Ola) display deficient responses to that stimulatory effects of mAb RP/14. |
| 别名 | Ly78; Ly-78; Lymphocyte antigen 78; RP105; Radioprotective 105 kDa protein |
| 同种亚型 | Rat WI, also known as Wistar (outbred) IgG2a< |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | BALB/c mouse splenocytes |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
