MS CD119 BV650 GR20 50UG
货号：
740498 基本售价：
7000.0 元 规格：
50ug
产品信息
概述| 货号 | 740498 |
| 描述 | The GR20 monoclonal antibody specifically binds to CD119, the α chain of the interferon γ(IFN-γ ) receptor. This receptor is expressed by mouse leukocytes, endothelial, and epithelial cells, but not by mature erythrocytes. GR20 mAb recognizes an epitope (susceptible to certain fixatives) in the ligand-binding site of the receptor. It can block the binding of mouse IFN- γ ; therefore, it can inhibit IFN- γ .mediated effects including the activation of mouse macrophages for tumor cell killing. IFN- γ has been reported to induce the expression of Ly-6A/E antigen on cell lines and normal B lymphocytes, and the GR20 antibody is capable of inhibiting the IFN- γ .induced expression of Ly-6A/E on the mouse B lymphoma line A20. The binding of the GR20 antibody to CD119 is inhibited by IFN- γ . This antibody reportedly does not have any agonist effect. |
| 别名 | Ifngr1; IFN-γ Receptor α; IFN-gamma R alpha; Ifngr; INF-g Receptor; Cd119 |
| 同种亚型 | Rat BN, also known as Brown Norway IgG2a |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | BALB/c mouse monomyelocytic cell line WEHI-3 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
