MS CD49B BV650 HMA2 50UG
货号：
740496 基本售价：
7000.0 元 规格：
50ug
产品信息
概述| 货号 | 740496 |
| 描述 | The HM α 2 antibody reacts with integrin α 2 chain (CD49b), the 150-kDa transmembrane glycoprotein that non-covalently associates with the integrin β 1 subunit (CD29) to form the integrin α2β 1 complex known as VLA-2. VLA-2, a receptor for collagen and laminin, is expressed on some splenic CD4+ T lymphocytes and NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, splenic NK cells, epithelial cells, and platelets; but it is not on thymocytes or Peyer’s-patch or lymphnode lymphocytes. The expression of VLA-2 is upregulated on lymphocytes in response to mitogens. The HM α 2 antibody has been reported to partially block the interaction of T-cell blasts, but not NK cells, with collagen. Purified HM α 2 mAb blocks the staining of splenic NK cells by the anti-CD49b/Pan-NK Cells mAb DX5 (Cat. No. 553858, for the PE conjugate). Therefore, mAb HM α 2 may be used like the DX5 mAb for identification of NK cells. |
| 别名 | Integrin α2 chain |
| 同种亚型 | Armenian Hamster IgG1, κ |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse colon carcinoma cell line Colon26 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
