MS CD125 BV605 T21 50UG
货号：
740429 基本售价：
7000.0 元 规格：
50ug
产品信息
概述| 货号 | 740429 |
| 描述 | The T21 monoclonal antibody specifically binds to CD125 which is also known as the alpha subunit of the IL-5 Receptor (IL5RA/IL-5R α ). CD125 is a type I transmembrane protein that belongs to the hemopoietin receptor and Ig gene superfamilies. It is expressed on B cells and eosinophils. CD125 associates with the Common β chain ( β c/Bc) subunit, also known as CD131, to form the functional IL-5 Receptor complex. Mouse IL-5 belongs to the hematopoietic growth factor family of cytokines and promotes the growth and differentiation of B cells and eosinophils. Upon binding, the T21 antibody blocks IL-5 binding to its receptor and can inhibit IL-5 induced B-cell proliferation and antibody production. |
| 别名 | Il5r; Il5ra; IL-5RA; IL-5Rα; IL-5R-alpha; IL-5R subunit alpha |
| 同种亚型 | Rat WI, also known as Wistar (outbred) IgG1 |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse T88-M Cell Line |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV605 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
