MS CD13 BV605 R3-242 50UG
货号:
740359 基本售价:
7000.0 元 规格:
50ug
产品信息
概述货号 | 740359 |
描述 | The R3-242 monoclonal antibody specifically binds to aminopeptidase N (APN), which has been reported to be the mouse CD13 homologue. APN is expressed in a variety of mammalian tissues, including intestinal and renal epithelial brush border, endothelium, liver, lung, and brain. In lymphoid tissues, R3-242 mAb is reported to detect APN on monocytes, macrophages, mast cells, dendritic cells, and B lymphocytes, but not on T cells, and thymocytes. However, the reported reactivity with B cells may be non-specific, via binding to the Fc γ receptors (CD16/CD32). This observation is in agreement with reports using different antibodies to mouse APN . APN may play a role in antigen presentation in the immune system. R3-242 mAb does not inhibit the enzymatic activity of APN. |
别名 | Anpep; Alanyl aminopeptidase; Aminopeptidase N; AP-N; mAPN; Lap-1 |
同种亚型 | Rat LEW, also known as Lewis IgG1 |
反应种属 | Mouse (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Crude Aminopeptidase N Preparation from BALB/c Mouse Intestinal Epithelium |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV605 under optimal conditions that minimize unconjugated dye and antibody.
|
存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |