MS CD26 BV421 H194-112 50UG
货号：
740021 基本售价：
7000.0 元 规格：
50ug
产品信息
概述| 货号 | 740021 |
| 描述 | The H194-112 monoclonal antibody specifically binds to CD26, which is also known as, Thymocyte-activating molecule (THAM), or dipeptidyl peptidase IV (DPP IV, Dpp4). CD26 is a ~220- kDa dimer formed of identical type-II transmembrane core polypeptides which undergo variable post-translational modifications. It is a multi-functional molecule with both ectopeptidase and signal-transducing activities. Studies with specific DPP IV inhibitors suggest that the enzymatic activity is involved in the mediation of T-cell activation events. The expression of CD26 is developmentally regulated in the thymus. Resting lymphoid cells of the bone marrow and peripheral B and T lymphocytes express low levels of CD26; bone-marrow and peritoneal myeloid cells do not. CD26 is also found on epithelial cells in the kidney, liver, small intestine, and lung. Cross-linked H194-112 mAb induces proliferation of immature and mature thymocytes in the presence of either IL-1 plus IL-2 or PMA; addition of IL-2 or IL-4 to PMA further enhances the activation. |
| 别名 | Cd26; Dpp4; dipeptidylpeptidase 4; THAM, DPP IV |
| 同种亚型 | Rat LOU, also known as Louvain, LOU/C, LOU/M IgG |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Cell-surface molecules solubilized from BALB/c mouse thymocytes |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV421 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
