Ms Rat CD42d Pure 1C2 500ug
货号：
552992 基本售价：
6950.0 元 规格：
500ug
产品信息
概述| 货号 | 552992 |
| 描述 | The 1C2 antibody reacts with CD42d (Platelet Glycoprotein V, GPV), a glycoprotein of 74 kDa in the mouse and 88 kDa in the rat. GPV noncovalently associates with GPIb (CD42b and c) and GPIX (CD42a) to form a receptor for von Willebrand factor on megakaryocytes and resting platelets. The binding sites for von Willebrand factor and thrombin have been localized to the GPIbachain (CD42b) of the GPIb-V-IX complex. GPV is cleaved by thrombin to release a 69-kDa soluble fragment, which contains the epitope recognized by mAb 1C2. The 1C2 antibody does not cross-react with human platelets nor with other hematopoietic cells of the mouse and rat. Anti-mouse CD41 mAb MWReg30 (Cat. No. 553848, for the FITC conjugate) may be used with mAb 1C2 to monitor mouse megakaryocyte maturation. |
| 别名 | Platelets and Megakaryocytes, Platelet Glycoprotein V |
| 同种亚型 | IgG3,λ1 |
| 反应种属 | Mouse, Rat (QC Testing) |
| 来源宿主 | Ar hamster |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | (C57BL/6 x DBA/2)F1 mouse platelets |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
