MS SPI-B PE U14-267 50UG
货号：
565834 基本售价：
6880.0 元 规格：
50ug
产品信息
概述| 货号 | 565834 |
| 描述 | The U14-267 monoclonal antibody specifically recognizes mouse Spi-B, that is encoded by Spib (Spi-B transcription factor (Spi-1/PU.1 related)). Spi-B belongs to the Ets family of transcription factors. It is expressed predominantly in B cells, T-cell progenitors, and plasmacytoid dendritic cells. Spi-B plays crucial roles in the development of T cells and plasmacytoid dendritic cells, and in the terminal differentiation of B cells. Although Spi-B deficient mice have normal numbers of B cells, they exhibit defects in germinal center formation and maintenance. In contrast, overexpression of Spi-B blocks plasma cell differentiation due to its capacity to repress Blimp-1 and Xbp-1 expression. |
| 别名 | SPI-B; Spib; Spi-1/PU.1 related; Ets transcription factor Spi-B |
| 同种亚型 | Rat IgG2a, κ |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Spi-B Recombinant Protein |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
