Ms Dndrtc Cells PerCP-Cy5.5 33D1 50ug
货号：
565222 基本售价：
6150.0 元 规格：
50ug
产品信息
概述| 货号 | 565222 |
| 描述 | The 33D1 antibody recognizes Dendritic cell inhibitory receptor 2 (Dcir2) which is also known as, Dendritic Cells antigen, Dendritic Cell (DC) Marker, or 33D1 antigen. This antigen is expressed on most dendritic cells of spleen, lymph node, and Peyers patch, but not liver, bone marrow, or epidermal dendritic cells; macrophages; other leukocytes; or erythroid cells. Within the spleen, the majority of 33D1+ DC are localized in the marginal zones. Thymic dendritic cells may express a low level of the 33D1 Antigen. It has been reported that bone-marrow DC can be induced to express the 33D1 antigen by culture in the presence of GM-CSF, and the resulting 33D1+ DC are effective in in vitro (induction of MLR) and in vivo (anti-tumoral vaccination) assays for antigen presentation. However, the addition of IL-4 to GM-CSF in bone-marrow cultures resulted in loss of 33D1 expression and enhanced the MLR-stimulatory activity of the DC. It has also been reported that 33D1 expression is upregulated when liver-derived DC are cultured on collagen-coated plates in the presence of GM-CSF. In vivo functional 33D1+ DC are induced in the brains of mice chronically infected with Toxoplasma gondii , probably via the parasites induction of GM-CSF. |
| 别名 | Dcir2; Dendritic Cell Marker; DC Marker; Dendritic Cells Ag; 33D1 Antigen |
| 同种亚型 | Rat SD, also known as Sprague-Dawley (outbred) IgG |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Dendritic cells purified from mouse spleen and lymph node |
| 标记 | PerCP-Cy5.5 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with PerCP-Cy5.5 under optimum conditions, and unconjugated antibody and free PerCP-Cy5.5 were removed. Storage of PerCP-Cy5.5 conjugates in unoptimized diluent is not recommended and may result in loss of signal intensity.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
