Ms Siglec-G PE-CF594 SH1 50ug
货号:
563337 基本售价:
6105.0 元 规格:
50ug
产品信息
概述货号 | 563337 |
描述 | The SH1 monoclonal antibody specifically binds to mouse Siglec-G (sialic acid binding immunoglobulin-like lectin G), also known as Siglec10. Siglec-G is a Type I transmembrane glycoprotein that belongs to the Immunoglobulin superfamily. Siglec-G functions as an adhesion molecule that mediates sialic-acid dependent binding to cells. Siglec-G is expressed on cells of the B cell lineage. Siglec-G is most highly expressed by pre-B cells and B1a cells within the B cell lineage and is not detectable on T cells. Siglec-G can inhibit B cell receptor-mediated calcium signaling when it is overexpressed. Mice that lack Siglec-G have significantly increased numbers of B1a cells that begins early in development and is B cell intrinsic. Siglec-G-deficient mice have higher titers of natural IgM antibodies than their normal counterparts. Mouse Siglec-G is the ortholog of human Siglec-10 (also known as, CD330). |
别名 | Siglecg; mSiglec-G; Siglec10; Siglec 10; CD330 |
同种亚型 | Mouse IgG1, κ |
反应种属 | Mouse (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Mouse Extracellular Siglec-G Recombinant Protein |
标记 | PE-CF594 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ PE-CF594 under optimum conditions, and unconjugated antibody and free PE-CF594 were removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |