Ms IL-21 Receptor PE 4A9 100ug
货号:
558607 基本售价:
5460.0 元 规格:
100ug
产品信息
概述货号 | 558607 |
描述 | The 4A9 monoclonal antibody specifically binds to CD360, which ia also known as the mouse IL-21 receptor (IL-21R). CD360 is a member of the cytokine receptor superfamily that closely resembles IL-2Rβ and IL-4Rα. The functional IL-21R , consisting of the IL-21R subunit and the common γ-chain, activates Jak-1, Jak-3, STAT1, STAT3, and STAT5 by binding the ligand, IL-21. The cellular response to ligand binding is complex being dependent on co-stimulation with other molecules and can result in either positive or negative regulatory signals . IL-21R is detected on developing T and B lymphocytes after commitment to each of these lineages with highest expression on mature and activated T and B lymphocytes. It has also been found to be involved in NK cell expansion. |
别名 | Cd360; Il21r; IL-21R; Interleukin 21 receptor; NILR; NR8; LR-beta |
同种亚型 | IgG2a,κ |
反应种属 | Mouse (QC Testing) |
来源宿主 | Rat |
使用方法 | FC |
性能供应商 | BD Pharmingen |
标记 | PE |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |