Ms VBta 17a TCR FITC KJ23 250ug
货号：
553212 基本售价：
5448.0 元 规格：
250ug
产品信息
概述| 货号 | 553212 |
| 描述 | The KJ23 antibody reacts with the V β 17[a] T-cell Receptor (TCR) of mice having the a haplotype (eg,C57L, SJL, SWR) of the Tcrb gene complex. Strains having the b (eg, A, AKR, BALB/c, CBA,C3H/He, C57BL, C58, DBA/1, DBA/2) Tcrb haplotype do not express functional V β 17 TCR, and the Tcrb-V17 gene locus is deleted in mice having the c (eg, RIII) haplotype. V β 17[a] TCR-bearing Tlymphocytes are clonally eliminated in mice expressing I-E (eg, C57BR). KJ23 antibody also recognizes two phenotypic variants of the V β 17[a] TCR: V β 17[a2] expressed in a variety of wild-derivedmouse strains and V β 17[a(cz)] expressed in Mtv -free CZ mice. The effects of Mtv -encoded superantigens upon V β 17[a] TCR-bearing T cells has been reviewed. Plate-bound KJ23 antibody activates V β 17[a] TCR-bearing T cells, and injection of the antibody can deplete V β 17[a]-bearing Tcells. |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse T cells |
| 标记 | FITC |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
