Ms CD107a BUV395 1D4B 50ug
货号:
565533 基本售价:
5400.0 元 规格:
50ug
产品信息
概述货号 | 565533 |
描述 | The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells. |
别名 | LAMP-1; LGP-120; LGP-A; P2B |
同种亚型 | Rat SD, also known as Sprague-Dawley (outbred) IgG |
反应种属 | Mouse (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Plasma membrane fraction of mouse embryo NIH 3T3 cell line |
标记 | BUV395 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BUV395 under optimum conditions, and unconjugated antibody and free BD Horizon™ BUV395 were removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |