Ms VAlp 8.3 TCR PE B21.14 100ug
货号：
553377 基本售价：
5320.0 元 规格：
100ug
产品信息
概述| 货号 | 553377 |
| 描述 | The B21.14 antibody reacts with some members of the V α8T-cellR eceptor (TCR) subfamily of mice having the a, b, c, andd haplotypes of the Tcra gene complex ( e.g ., all strains tested). It recognizes an epitope in the CDR1 of V α 8.3, but not V α 8.2, TCR subfamily member, as does the KT50 mAb (Cat. No. 557096, for the biotinylated antibody). Site-directed mutagenesis has identified three amino acids which are necessary for antibody reactivity and which are unique to V α 8.3 among the five functional V α 8 TCR subfamily members. On a common H-2K[k] background and using the KT50 mAb, the frequency of V α 8.3 TCR-bearing T lymphocytes has been demonstrated to be higher in Tcra[a/a] mice than in Tcra[a/b] mice. Furthermore, studies of congenic strains suggest that CD8+ V α 8.3 TCR-bearing T lymphocytes undergo negative selection in mice expressing MHC class I antigens of the H-2[d]haplotype. |
| 同种亚型 | IgG1,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Soluble αβ TCR from mouse cytotoxic T-cell clone CW3/1.1 |
| 标记 | PE |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
