Ms CD281 (TLR1) BV421 TR23 50ug
货号：
565792 基本售价：
5170.0 元 规格：
50ug
产品信息
概述| 货号 | 565792 |
| 描述 | The TR23 monoclonal antibody specifically binds to CD281, which is also known as Toll-like receptor 1 (TLR1), or Toll/interleukin-1 receptor-like protein (TIL). CD281 is an ~98 kDa type I transmembrane glycoprotein that belongs to the Toll-like receptor (TLR) family. CD281 functions as a pattern recognition receptor (PRR) for pathogen-associated molecular patterns (PAMP) that are broadly expressed by microbial pathogens and plays essential roles in innate and adaptive immunity. In the process of binding microbial ligands, such as triacylated microbial lipopeptides, TLR1 associates with CD282 (TLR2). CD281 is expressed on B cells, monocytes/macrophages, and dendritic cells. CD281/TLR1-deficient mice display impaired production of inflammatory cytokines in response to microbial ligands. |
| 别名 | Cd281; Tlr1; Toll-like receptor 1; TIL; Toll/interleukin-1 receptor-like |
| 同种亚型 | Rat WI, also known as Wistar (outbred) IgG2a< |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse TLR1 Transfected Cell Line |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
