Ms CD282 (TLR2) BV421 CB225 50ug
货号：
565908 基本售价：
5060.0 元 规格：
50ug
产品信息
概述| 货号 | 565908 |
| 描述 | The CB225 monoclonal antibody specifically binds to the mouse Toll like receptor 2 (TLR2) which is also known as, CD282. CD282 is a type 1 transmembrane glycoprotein and TLR family member. TLR2 forms heterodimers with either TLR1 or TLR6, and is expressed on monocytes, macrophages, dendritic cells, granulocytes, endothelial cells, or epithelial cells. This pattern recognition receptor is important for sensing and transducing signals in response to microbial cell wall components including lipoproteins, peptidoglycans, and lipoteichoic acid. CD282 signals through intracellular MYD88 and TRAF6 leading to NF-kappa-B activation and the production of cytokines and inflammatory mediators by responding cells. TLR2 plays a major role in mediating inflammatory and innate immune responses to many microbial pathogens. |
| 别名 | TLR2; Tlr2; Toll-like receptor 2; Ly105 |
| 同种亚型 | Rat WI, also known as Wistar (outbred) IgG2a< |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse TLR2 Transfected Cell Line |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
|
| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
