Ms TLT-2 (Treml2) BV421 MIH47 50ug
货号:
564185 基本售价:
4950.0 元 规格:
50ug
产品信息
概述货号 | 564185 |
描述 | The MIH47 monoclonal antibody specifically binds to Trem-like transcript 2 protein (TLT-2) which is also known as TREML2 (Triggering receptor expressed on myeloid cells-like 2). TLT-2 is a type I transmembrane protein that belongs to the TREM family. It consists of a single extra-cellular Ig-like V-type domain, a transmembrane segment and a cytoplasmic tail and reportedly serves as a receptor for B7-H3/CD276. It is expressed on most B cells, CD8+ T cells, activated CD4+ T cells, macrophages and granulocytes and at low levels by some NK cells and dendritic cells. TLT-2 can reportedly serve costimulatory and coinhibitory functions in the immune system. TLT-2 expression is upregulated on neutrophils and macrophages in response to inflammatory conditions in vivo. TLT-2 serves as engulfment receptor for apoptotic cells and plays roles in both innate and adaptive immunity. |
别名 | B7-H3 receptor; Tlt2; TRML2; Trem-like transcript 2 protein; Gm750 |
同种亚型 | Rat IgG2a, κ |
反应种属 | Mouse (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Mouse TLT-2 Recombinant Protein |
标记 | BV421 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
|
存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |