Ms CD48 APC HM48-1 50ug
货号：
562746 基本售价：
4600.0 元 规格：
50ug
产品信息
概述| 货号 | 562746 |
| 描述 | The HM48-1 monoclonal antibody specifically binds to CD48 (previously known as BCM1 in mice, Blast-1 in human, and OX-45 in the rat), a GPI-anchored member of the Ig superfamily. It is widely distributed on leukocytes, but not on non-hematopoietic cells, and its ligands include CD2 (LFA-2) and CD244 (2B4 antigen). The HM48-1 mAb blocks binding of soluble CD2 to CD48-bearing cells, blocks the interaction of CD2 and CD244, inhibits spleen cell proliferative responses to mitogens, augments the proliferative response of spleen cells when cross-linked with anti-CD3e mAbs, and inhibits priming of CTL in vitro. In vivo administration of HM48-1 antibody can prolong survival of cardiac allografts, an effect which is greatly enhanced by the addition of anti-CD2 mAb 12-15. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes. |
| 别名 | BLAST; BLAST-1; BCM1; HM48-1; MEM-102; Sgp-60; SLAMF2 |
| 同种亚型 | Armenian Hamster IgG1, λ3 |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse T lymphoma MBL-2 |
| 标记 | APC |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
