Ms Galectin-9 BV421 RG9-35 50ug
货号：
566028 基本售价：
4590.0 元 规格：
50ug
产品信息
概述| 货号 | 566028 |
| 描述 | The RG9-35 monoclonal antibody specifically binds to Galectin 9 (Gal-9) which is encoded by Lgals9 (lectin, galactose binding, soluble 9). Galectin-9 is expressed within cells and can be conveyed to the cell surface and released in soluble form. It is expressed by various cell types including lymphocytes, thymocytes, macrophages, dendritic cells, astrocytes, mast cells, eosinophils, fibroblasts, epithelial cells, and endothelial cells. Its expression can be induced by cells in response to proinflammatory cytokines or infection by certain viruses. Galectin-9 is a ~ 40 kDa S-type lectin that has two carbohydrate recognition domains (CRDs) and forms homodimers . It binds to β-galactosides a nd can serve as a ligand for TIM-3 (CD366). Galectin-9 can play multiple roles in innate and adaptive immune responses including the activation of macrophage cytokine secretion and bactericidal functions, promotion of dendritic cell maturation, regulatory T cell expansion, and negative regulation of Th1, Th17, NK, and cytotoxic T cells. The RG9-35 antibody can reportedly block some biological activities of Galectin-9. |
| 别名 | Galectin9; Gal-9; Gal9; Lgals9; LEG9 |
| 同种亚型 | Rat IgG2a, κ |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Galectin-9 Recombinant Protein |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
