Ms VDta 6.3/2 TCR PE 8F4H7B7 100ug
货号：
555321 基本售价：
4370.0 元 规格：
100ug
产品信息
概述| 货号 | 555321 |
| 描述 | The 8F4H7B7 antibody reacts with V δ 6.3/2 T-cell Receptor (TCR)-bearing T lymphocytes. Originally defined as a member of the V δ 6 TCR subfamily, it is now proposed that the C57BL-derived V δ 6.3 is an allelic variant of V δ 6.2, found in A/J, AKR, BALB/c, C3H/He, and FVB mice. mAb 8F4H7B7 crossreacts with V δ 6.4 and possibly V δ 6.6 in DBA/2 mice, and it also detects a subset of γδ TCR-bearing cells in CBA/J and C57L mice. It does not recognize V δ 4, V δ 5, V δ 6.1, or V δ 6.5 TCR. A subpopulation of thymocytes expressing V δ 6.3 or V δ 6.4 TCR (in C57BL/6 or DBA/2 mice, respectively) and low levels of CD90.2 (Thy-1.2) shares functional and phenotypic characteristics with NK-T cells. Similar δ V 6.4 TCRexpressing lymphocytes make up significant proportions of the γδ T-cell populations in the liver and spleen of DBA/2 mice. Furthermore, T lymphocytes bearing V δ 6.3/2 TCR are found in the skin and intestinal epithelium and may represent a unique T-cell subpopulation with a potential for autoimmune reactivity. |
| 同种亚型 | IgG2,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Ar hamster |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | 1E6.11.D7, a C57BL/6 mouse Vγ1.1Vδ6.3 TCR-bearing IEL/T-cell hybridoma |
| 标记 | PE |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
