Ms CD278 Alexa 647 7E.17G9 50ug
货号:
563469 基本售价:
4060.0 元 规格:
50ug
产品信息
概述货号 | 563469 |
描述 | The 7E.17G9 antibody reacts with CD278, the InducibleCostimulatory molecule (ICOS), a 47-57 kDa homodimeric glycoprotein of the CD28 family of costimulatory molecules. ICOS is expressed on subpopulations of CD4-CD8- and CD4+CD8- (but not CD4-CD8+ or CD4+CD8+) thymocytes, on some T-cell lines, and on small numbers of peripheral leukocytes. It is upregulated on T lymphocytes following activation via the T-cell receptor. The T-cell activation marker H4 is the same molecule asICOS. ICOS is a costimulatory receptor, and its ligand on antigen-presenting cells has been called B7RP-1, GL50, B7h, B7-H2, or LICOS. There is considerable evidence that the interaction of ICOS with its ligand is involved in the regulation of many, but not all, T-cell-mediated immune responses. |
别名 | ICOS; Ailim; CCLP; CRP-1; Ly115; Inducible T-cell costimulator |
同种亚型 | Rat IgG2b, κ |
反应种属 | Mouse (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Mouse Icos cDNA and ICOS hexahistidine fusion protein |
标记 | Alexa Fluor 647 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
|
存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |