Ms CD131 PE JORO50 200ug
货号：
559920 基本售价：
4056.0 元 规格：
200ug
产品信息
概述| 货号 | 559920 |
| 描述 | The JORO50 monoclonal antibody specifically recognizes the extracellular regions of the mouse CD131/ βc (Bc, AIC2B, Il3rb1, Csf2rb1) and βIL3 (BIL3, AIC2A, Il3rb2, Csf2rb2) cytokine receptor subunits. A variety of mouse cell ty pes, including multipotential hematopoietic stem cells, mast cells, megakaryocytes, eosinophils, erythroblasts, pre-B cells, and osteoclasts, express βIL-3 and βc subunits. Either βIL-3 or βc can combine with the IL-3Rα chain to form two distinct, functional (i.e., signaling), high affinity receptors for mouse IL-3. The βIL-3 subunit by itself can bind mouse IL-3 with low affinity whereas the βc subunit can not. βc (but not βIL-3) can combine with the IL-5Rα (CD125) and GM-CSFRα (CD116) subunits to form hig h affinity, signaling receptors for mouse IL-5 or GM-CSF, respectively. The immunogen used to generate the JORO50 hybridoma was the bone marrow-derived, C4-77 pro-T lymphocyte clone. |
| 别名 | CD131, βc, Bc, AIC2B, Il3rb1, Csf2rb1; βIL3, BIL3, AIC2A, Il3rb2, Csf2rb2 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Bone Marrow-Derived C4-77 Pro-T Lymphocyte Clone |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
