Ms H2-M3 Pure 130 100ug
货号：
551769 基本售价：
3990.0 元 规格：
100ug
产品信息
概述| 货号 | 551769 |
| 描述 | The hamster anti-mouse H2-M3 antibody (clone 130) reacts with the H2-M3 major histocompatibility complex (MHC) non-classical class Ib antigen. H2-M3 (M3) associates with β 2-microglobulin and is capable of being expressed by most leukocytes. However, due to a lack of endogenous antigens, M3 has been reported to be undetectable on most cells. Its expression is induced by high-affinity N -formylated peptides from mitochondria, Listeria monocytogenes , and Mycobacterium tuberculosis . The induced expression of M3 is most efficient on antigen presenting cells. M3 presents antigen to cytotoxic T lymphocytes and may play a key role in protective immunity against the intracellular bacteria L. monocytogenesandM. tuberculosis . Furthermore, M3 is capable of presenting mitochondrial antigens for intrathymic positive selection of T-cell receptors which recognize those peptides. |
| 同种亚型 | IgG1,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Ar hamster |
| 使用方法 | FC, IP |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Purified soluble complex of recombinant truncated M3 and β2-microglobulin |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
