Ms CD74 FITC In-1 500ug
货号:
555318 基本售价:
3936.0 元 规格:
500ug
产品信息
概述货号 | 555318 |
描述 | The In-1 monoclonal antibody specifically binds to CD74, the MHC class II-associated Invariant chain (Ii), expressed in I-A+ cell populations. Although it is predominantly expressed intracellularly, it has also been detected on the cell surface of some B-cell lines and at low levels on a small number of B lymphocytes. In the mouse, alternatively spliced transcripts encode 31-kDa and 41-kDa isoforms, and the cell-surface CD74 has a chondroitin sulfate side chain which allows it to interact with CD44. CD74 is directly involved in the intracellular transport of MHC class II molecules and antigen presentation, and it affects the maturation of T and B lymphocytes. |
别名 | Cd74; CLIP; Ii; Ia-associated invariant chain; Ia-GAMMA; DHLAG; HG2A; HLADG |
同种亚型 | IgG2b,κ |
反应种属 | Mouse (QC Testing) |
来源宿主 | Rat |
使用方法 | IC/FC |
性能供应商 | BD Pharmingen |
免疫原 | A.TL mouse lymphocytes and B10.A mouse-derived CH1 B-cell lymphoma |
标记 | FITC |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |