Ms VBta 6 TCR Biotin RR4-7 250ug
货号：
553192 基本售价：
3632.0 元 规格：
250ug
产品信息
概述| 货号 | 553192 |
| 描述 | The RR4-7 antibody reacts with the Vβ 6 T-Cell Receptor (TCR) of mice having the a(e.g.,C57BR, C57L, SJL) and b(e.g.,A, BALB/c, CBA/Ca, C3H/He, C57BL, DBA/1) haplotypes of the Tcrb gene complex. The Tcrb-V6gene locus is deleted in mice having the c(e.g.,RIII) haplotype. Vβ 6 TCR-bearing T lymphocytes are clonally eliminated in mice expressing superantigen encoded by Mtv-7(Mls-1[a], Mls[a]) endogenous provirus (e.g.,AKR, CBA/J, C58, DBA/2, NZB), or Mtv-43 endogenous provirus (e.g.,MA/MyJ). Exogenous MMTV-SW, as well as endogenous Mtv-44-encoded superantigen (e.g.,NZW), also causes incomplete elimination of Vβ 6 TCR-expressing T cells. Plate-bound RR4-7 antibody activates Vβ 6 TCR-bearing T cells, soluble RR4-7 mAb blocks in vitro proliferation and cytolytic activities of Vβ 6 TCR-bearing T-cell clones, and injection of the antibody results in in vivo depletion of Vβ 6 TCR-bearing T cells. |
| 同种亚型 | IgG2b,λ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | C57BL/6 Mouse Helper T-Cell Clone OI11 |
| 标记 | Biotin |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
