Ms CD282 Alexa 647 6C2 50ug
货号:
562625 基本售价:
3500.0 元 规格:
50ug
产品信息
概述货号 | 562625 |
描述 | The 6C2 monoclonal antibody specifically binds to the mouse Toll like receptor 2 (TLR2) that is also known as CD282. CD282 is a type 1 transmembrane glycoprotein and a TLR family member. It is expressed on the surface of monocytes, macrophages, dentritic cells, granulocytes, endothelial and epithelial cells. This pattern recognition receptor is important for sensing and transducing signals in response to microbial cell wall components including lipoproteins, peptidoglycans and lipoteichoic acid. CD282 signals through intracellular MYD88 and TRAF6 leading to NF-kappa-B activation and the production of cytokines and inflammatory mediators by responding cells. TLR2 plays a major role in mediating inflammatory and innate immune responses. |
别名 | TLR2; Tlr2; Toll-like receptor 2; Ly105 |
同种亚型 | Rat IgG2b, κ |
反应种属 | Mouse (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Mouse TLR2 Transfected Cell Line |
标记 | Alexa Fluor 647 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |