Ms CD36 APC CRF D-2712 100ug
货号:
562744 基本售价:
3190.0 元 规格:
100ug
产品信息
概述货号 | 562744 |
描述 | The CRF D-2712 monoclonal antibody specifically binds to mouse and rat CD36, an 88-kDa glycoprotein member of the class B scavenger receptor family. CD36 is a multifunctional receptor that has a variety of ligands and is expressed on many cell types. Consequently, it is known by several names, including macrophage scavenger receptor, platelet glycoprotein IV, and fatty acid translocase. Cells that express CD36 include platelets, megakaryocytes, monocytes/macrophages, dendritic cells, erythroid precursors, microvascular endothelia, skeletal, cardiac, and smooth muscle cells, adipocytes, and epithelia of retina, breast, and intestine. This multi-ligand receptor functions in the clearance of apoptotic cells and abnormal erythrocytes (in malaria and sickle-cell anemia), the transport of long-chain fatty acids and oxidized low-density lipoproteins, the regulation of angiogenesis by mediating the effects of thrombospondin-1, and the mediation of coronary vasoconstriction. Crosslinking of cell-surface CD36 with plate-bound CRF D-2712 antibody promotes internalization of photoreceptor outer segment fragments by cultured retinal pigment epithelium. |
别名 | Platelet glycoprotein 4; PAS-4; GPIIIB; Fatty acid translocase; Scavenger R |
同种亚型 | Mouse Cd36 null IgA, κ |
反应种属 | Mouse (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Recombinant mouse CD36 |
标记 | APC |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |