Ms CD4 IHC Pure H129.19 1mL
货号：
550278 基本售价：
3000.0 元 规格：
1mL
产品信息
概述| 货号 | 550278 |
| 描述 | The H129.19 monoclonal antibody specifically binds to the CD4 (L3T4) differentiation antigen expressed on thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells of all mouse strains tested. CD4 has also been detected on pluirpotent hematopoietic stem cells, bone marrow myeloid precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 is expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine Lck. The H129.19 antibody blocks binding of the anti-mouse CD4 antibodies GK1.5 and RM4-5, but not RM4-4 antibody. mAb H129.19 inhibits various responses of T helper cells to antigenic or mitogenic stimuli. |
| 别名 | Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3 |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | IHC(Fr), IHC(Zn) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | A.TH mouse CTL clone A15.1.17 |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide. |
| 浓度 | 62.5 µg/ml |
