Ms CD18 Pure GAME-46 100ug
货号：
557440 基本售价：
2997.0 元 规格：
100ug
产品信息
概述| 货号 | 557440 |
| 描述 | The GAME-46 antibody reacts with the common β 2 chain of LFA-1 (CD11a/CD18, αLβ 2 integrin), Mac-1 (CD11b/CD18, αMβ 2 integrin), and gp150, 95 (CD11c/CD18, αXβ 2 integrin). Expression of CD18 is limited to leukocytes, where it is widely distributed in consort with each of the three integrin α chains (CD11a, CD11b, and CD11c). Among splenocytes, NK cells have the highest density of CD18, and T lymphocytes express a higher density than the remaining cells. The β 2 integrins are important mediators of leukocyte-endothelium interactions. It has been reported that GAME-46 antibody blocks in vitro adhesion of LFA-1-expressing cells to the ligands ICAM-1, ICAM-2 and ICAM-3 and of Mac-1-expressing cells to ICAM-1, C3bi, and fibrinogen. |
| 别名 | Integrin β2 chain |
| 同种亚型 | IgG1,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | LFA-1 (CD11a/CD18) from mouse T-cell hybridoma TAM8C41 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
