MS CD11C APC-R700 N418 25UG
货号：
565871 基本售价：
2940.0 元 规格：
25ug
产品信息
概述| 货号 | 565871 |
| 描述 | The N418 monoclonal antibody specifically binds to CD11c, the Integrin alpha X (Integrin α X, Itgax) chain of the heterodimeric gp150, 95 (CD11c/CD18, αXβ2 ) integrin that forms the complement receptor 4 (CR4). CD11c is a150 kDa type I transmembrane glycoprotein that is expressed on dendritic cells, CD4-CD8+ intestinal intraepithelial lymphocytes (IEL), and some NK cells and T cells. CD11c expression is upregulated on IEL and T cells following activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. The CD11c/CD18 integrin can bind to several ligands including iC3b, fibrinogen, and CD54. This integrin reportedly plays important roles in phagocytosis and in mediating cellular interactions during inflammation. |
| 别名 | Itgax; Integrin alpha-X; Integrin αX; ITAX; CR4; Complement Receptor 4 |
| 同种亚型 | Armenian Hamster IgG2 |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Dendritic Cells |
| 标记 | APC-R7 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon APC-R700 under optimum conditions, and unconjugated antibody and free BD Horizon APC-R700 were removed.
|
| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
