Ms VBta 6 TCR PE RR4-7 100ug
货号：
553194 基本售价：
2700.0 元 规格：
100ug
产品信息
概述| 货号 | 553194 |
| 描述 | The RR4-7 antibody reacts with the V β 6 T-Cell Receptor (TCR) of mice having the a(e.g., C57BR, C57L, SJL) and b(e.g., A, BALB/c, CBA/Ca, C3H/He, C57BL, DBA/1) haplotypes of the Tcrb gene complex. The Tcrb-V6 gene locus is deleted in mice having the c(e.g., RIII) haplotype. V β 6 TCR-bearing T lymphocytes are clonally eliminated in mice expressing superantigen encoded by Mtv-7(Mls-1[a], Mls[a] ) endogenous provirus ( e.g., AKR, CBA/J, C58, DBA/2, NZB), or Mtv -43 endogenous provirus ( e.g., MA/MyJ). Exogenous MMTV-SW, as well as endogenous Mtv -44-encoded superantigen ( e.g., NZW), also causes incomplete elimination of V β 6 TCR-expressing T cells. Plate-bound RR4-7 antibody activates V β 6 TCR-bearing T cells, soluble RR4-7 mAb blocks in vitro proliferation and cytolytic activities of V β 6 TCR-bearing T-cell clones, and injection of the antibody results in in vivo depletion of V β 6 TCR-bearing T cells. |
| 同种亚型 | IgG2b,λ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | C57BL/6 Mouse Helper T-Cell Clone OI11 |
| 标记 | PE |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
