Ms IL-10 APC JES5-16E3 25ug
货号:
561059 基本售价:
1272.0 元 规格:
25ug
产品信息
概述货号 | 561059 |
描述 | The JES5-16E3 monoclonal antibody specifically binds to the mouse cytokine, Interleukin-10 (IL-10). IL-10 is also known as Cytokine Synthesis Inhibitory Factor (CSIF). It is produced by various activated cell types including CD4+ T cells, CD8+ T cells, T regulatory cells, NK T cells, B1 B cells, NK cells, macrophages, dendritic cells, mast cells, granulocytes and keratinocytes. IL-10 plays a pivotal role in regulating immune responses and protecting the host from damage caused by inflammatory and autoimmune responses. IL-10 has numerous biological activities including the inhibition of cytokine synthesis by activated T cells, NK cells, monocytes, and macrophages. In the presence of accessory cells, IL-10 inhibits mitogen- or anti-CD3 induced proliferation of T lymphocytes. IL-10 has also been shown to costimulate the development of thymocytes, B cell differentiation and the generation of cytotoxic T cells. The immunogen used to generate the JES5-16E3 hybridoma was recombinant mouse IL-10. JES5-16E3 is a neutralizing antibody. |
同种亚型 | IgG2b |
反应种属 | Mouse (QC Testing) |
来源宿主 | Rat |
使用方法 | IC/FC |
性能供应商 | BD Pharmingen |
免疫原 | Recombinant mouse IL-10 |
标记 | APC |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |