Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab
Sci Rep, 2016;6(0):31726.
Species: Human
Sample Type: Whole Blood
Application: Isotype control
An essential receptor for adeno-associated virus infection.
Authors: Pillay S, Meyer N, Puschnik A, Davulcu O, Diep J, Ishikawa Y, Jae L, Wosen J, Nagamine C, Chapman M, Carette J
Nature, 2016;530(7588):108-12.
Species: Human
Sample Type: Whole Cells
Application: Flow
Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Gu�rin in Glucocorticoid-Treated Human Macrophages
Authors: Julia Steiger
J Immunol, 2016;197(1):222-32.
Species: Human
Sample Type: Whole Cells
Application: Flow
Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.
Authors: Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J
Stem Cells, 2015;33(1):133-45.
Species: Human
Sample Type: Whole Cells
Application: Flow control
Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner.
Authors: Anguille S, Van Acker H, Van den Bergh J, Willemen Y, Goossens H, Van Tendeloo V, Smits E, Berneman Z, Lion E
PLoS ONE, 2015;10(5):e0123340.
Species: Human
Sample Type: Whole Cells
Application: Flow
IL-17A Contributes to the Pathogenesis of Endometriosis by Triggering Proinflammatory Cytokines and Angiogenic Growth Factors.
Authors: Ahn S, Edwards A, Singh S, Young S, Lessey B, Tayade C
J Immunol, 2015;195(6):2591-600.
Species: Human
Sample Type: Whole Cells
Application: Flow
Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.
Authors: Le Q, Blanchet M, Seidah N, Labonte P
J Biol Chem, 2015;290(38):23385-400.
Species: Human
Sample Type: Whole Cells
Application: Flow
Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
Eur J Immunol, 2015;45(10):2937-44.
Species: Human
Sample Type: Whole Cells
Application: Flow
The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages.
Authors: Warat M, Sadowski T, Szliszka E, Krol W, Czuba Z
Molecules, 2015;20(1):900-12.
Species: Mouse
Sample Type: Whole Cells
Application: Flow control
Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor x c-MET Bispecific Antibody.
Authors: Jarantow S, Bushey B, Pardinas J, Boakye K, Lacy E, Sanders R, Sepulveda M, Moores S, Chiu M
J Biol Chem, 2015;290(41):24689-704.
Species: Human
Sample Type: Whole Cells
Application: Isotype control
Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.
Authors: Mercer J, Argus J, Crabtree D, Keenan M, Wilks M, Chi J, Bensinger S, Lavau C, Wechsler D
PLoS ONE, 2015;10(6):e0129776.
Species: Human
Sample Type: Whole Cells
Application: Flow
Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma.
Authors: Kim, Seong Mu, Woo, Ji Sun, Jeong, Chang Hy, Ryu, Chung He, Jang, Jae-Deog, Jeun, Sin-Soo
Stem Cells Transl Med, 2014;3(2):172-82.
Species: Human
Sample Type: Whole Cells
Application: Flow control
Metabolic impact of anti-angiogenic agents on U87 glioma cells.
Authors: Mesti T, Savarin P, Triba M, Le Moyec L, Ocvirk J, Banissi C, Carpentier A
PLoS ONE, 2014;9(6):e99198.
Species: Human
Sample Type: Whole Cells
Application: Isotype control
Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells.
Authors: Mancini M, Gariboldi M, Taiana E, Bonzi M, Craparotta I, Pagin M, Monti E
Br J Cancer, 2014;110(12):2865-73.
Species: Human
Sample Type: Whole Cells
Application: Flow control
The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Authors: Mimura, Kousaku, Shiraishi, Kensuke, Mueller, Anja, Izawa, Shinichi, Kua, Ley-Fang, So, Jimmy, Yong, Wei-Peng, Fujii, Hideki, Seliger, Barbara, Kiessling, Rolf, Kono, Koji
J Immunol, 2013;191(12):6261-72.
Species: Human
Sample Type: whole cells
Application: Flow control
Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis.
Authors: Andersson S, Svensson M, Erlandsson M, Dehlin M, Andersson K, Bokarewa M
PLoS ONE, 2012;7(10):e47668.
Species: Mouse
Sample Type: Whole Cells
Application: Ctrl
Clinical and functional characterization of a patient carrying a compound heterozygous pericentrin mutation and a heterozygous IGF1 receptor mutation.
Authors: Muller E, Dunstheimer D, Klammt J, Friebe D, Kiess W, Kratzsch J, Kruis T, Laue S, Pfaffle R, Wallborn T, Heidemann PH
PLoS ONE, 2012;7(5):e38220.
Species: Human
Sample Type: Whole Cells
Application: Flow
The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells.
Authors: Szliszka E, Helewski KJ, Mizgala E, Krol W
Int. J. Oncol., 2011;39(4):771-9.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance.
Authors: Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DA
J. Immunol., 2011;186(12):6661-6.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells.
Authors: Ball SG, Bayley C, Shuttleworth CA, Kielty CM
Biochem. J., 2010;427(1):29-40.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Authors: Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R
Int. J. Cancer, 2009;125(1):212-21.

Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma.
Authors: Heath DJ, Chantry AD, Buckle CH, Coulton L, Shaughnessy JD, Evans HR, Snowden JA, Stover DR, Vanderkerken K, Croucher PI
J. Bone Miner. Res., 2009;24(3):425-36.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy.
Authors: Sveinbjornsson B, Rasmuson A, Baryawno N, Wan M, Pettersen I, Ponthan F, Orrego A, Haeggstrom JZ, Johnsen JI, Kogner P
FASEB J., 2008;22(10):3525-36.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
Authors: Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A
J. Immunol., 2007;178(12):8064-72.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
VEGFR2 expressing circulating (progenitor) cell populations in volunteers and cancer patients.
Authors: Vroling L, Yuana Y, Schuurhuis GJ, van Hinsbergh VW, Gundy C, de Haas R, van Cruijsen H, Boven E, Hoekman K, Broxterman HJ
Thromb. Haemost., 2007;98(2):440-50.
Species: Human
Sample Type: Whole Blood
Application: Ctrl
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
Authors: Ball SG, Shuttleworth CA, Kielty CM
J. Cell Biol., 2007;177(3):489-500.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
Authors: Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA
J. Thromb. Haemost., 2005;3(4):733-41.
Species: Human
Sample Type: Whole Cells
Application: Flow
Analysis of CD4+ T-Cell responses to a novel alpha-fetoprotein-derived epitope in hepatocellular carcinoma patients.
Authors: Alisa A, Ives A, Pathan AA, Navarrete CV, Williams R, Bertoletti A, Behboudi S
Clin. Cancer Res., 2005;11(18):6686-94.
Species: Human
Sample Type: Whole Cells
Application: Ctrl
Different domains of Pseudomonas aeruginosa exoenzyme S activate distinct TLRs.
Authors: Epelman S, Stack D, Bell C, Wong E, Neely GG, Krutzik S, Miyake K, Kubes P, Zbytnuik LD, Ma LL, Xie X, Woods DE, Mody CH
J. Immunol., 2004;173(3):2031-40.
Species: Human
Sample Type: Whole Cells
Application: Flow
Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study.
Authors: Dror Y, Durie P, Ginzberg H, Herman R, Banerjee A, Champagne M, Shannon K, Malkin D, Freedman MH
Exp. Hematol., 2002;30(7):659-69.
Species: Human
Sample Type: Whole Cells
Application: Flow

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

• New Tools: NorthernLights New Fluorescent Secondary Antibodies