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货号： bs-5108R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-5108R
- 英文名称
- PNPO
- 中文名称
- 磷酸吡哆醇氧化酶抗体
- 别 名
- PDXPO; PNPO; PNPO_HUMAN; Pyridoxal 5 phosphate synthase; pyridoxamine 5 phosphate oxidase; Pyridoxamine phosphate oxidase; Pyridoxamine-phosphate oxidase; pyridoxine 5 phosphate oxidase; Pyridoxine-5-phosphate oxidase; EC 1.4.3.5; FLJ10535.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 细胞定位
- 细胞核 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PNPO:41-140/261
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Catalyzes the oxidation of either pyridoxine 5-phosphate (PNP) or pyridoxamine 5-phosphate (PMP) into pyridoxal 5-phosphate (PLP).
Function:
Catalyzes the oxidation of either pyridoxine 5-phosphate (PNP) or pyridoxamine 5-phosphate (PMP) into pyridoxal 5-phosphate (PLP).
Subunit:
Homodimer.
DISEASE:
Defects in PNPO are the cause of pyridoxine-5-phosphate oxidase deficiency (PNPO deficiency) [MIM:610090]; also known as PNPO-related neonatal epileptic encephalopathy. The main feature of neonatal epileptic encephalopathy is the onset within hours of birth of a severe seizure disorder that does not respond to anticonvulsant drugs and can be fatal. Seizures can cease with the administration of PLP, being resistant to treatment with pyridoxine.
Similarity:
Belongs to the pyridoxamine 5-phosphate oxidase family.
SWISS:
Q9NVS9
Gene ID:
55163
Database links:Entrez Gene: 55163 Human
Entrez Gene: 103711 Mouse
Entrez Gene: 64533 Rat
Omim: 603287 Human
SwissProt: Q9NVS9 Human
SwissProt: Q91XF0 Mouse
SwissProt: O88794 Rat
Unigene: 631742 Human
Unigene: 254704 Mouse
Unigene: 158883 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PNPO是维生素B6(VB6)代谢的关键酶，参与催化氨基酸代谢的各种反应和其它多种代谢过程。
- 产品图片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-PNPO Polyclonal Antibody, Unconjugated(bs-5108R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining