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货号: bs-2393R 基本售价: 780.0 元 规格: 50ul
- 规格:50ul
- 价格:780.00元
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-2393R
- 英文名称
- TRPC6
- 中文名称
- 瞬时受体电位离子通道蛋白6抗体
- 别 名
- MTRP6; Short transient receptor potential channel 6; si:rp71-1p14.9; Transient Receptor Potential Cation Channel Subfamily C Member 6; Transient receptor protein 6; TRP 6; TRP-6; TRP6; TRPC 6; TrpC6; TRPC6_HUMAN; TRRP6; bZ1P14.9; FLJ11098; FLJ14863; FSGS2.
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学 通道蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=0.2μg/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 106kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TRPC6:651-750/931 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq].
Subunit:
Interacts with MX1 and RNF24.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.
Similarity:
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily.
Contains 4 ANK repeats.
SWISS:
Q9Y210
Gene ID:
7225
Database links:Entrez Gene: 7225 Human
Entrez Gene: 22068 Mouse
Entrez Gene: 89823 Rat
Omim: 603652 Human
SwissProt: Q9Y210 Human
SwissProt: Q61143 Mouse
Unigene: 159003 Human
Unigene: 325086 Mouse
Unigene: 105986 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
- blank control(blue): U937 cells (fixed with 4% paraformaldehyde)
Isotype control(orange): Cell lines treated with rabbit IgG (bs-0295P)instead of the primary antibody to confirm that primary antibody binding is specific. primary antibody(Green):Rabbit Anti-CD162 antibody(bs-2301R),Concebtration: 0.2μg/10^6 cells
Secondary only control(light blue): Both cell lines treated with Goat Anti-rabbit IgG/FITC antibody (bs-0295G-FITC) to confirm no background signal produced from secondary antibody alone.