Human Noggin, research grade (100 µg)
货号：
130-103-456 基本售价：
询价 规格：
100 μg
产品信息
概述| 货号 | 130-103-456 |
| 描述 | Human Noggin is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. |
性能| 供应商 | Miltenyi |
| 背景 | Noggin is a disulfide-linked homodimer that acts by binding members of the TGF-β family, and consequently blocks their ability to signal through their receptors. Noggin plays a crucial role in regulating developmental processes by inhibiting the signaling pathway of bone morphogenetic protein 4 (BMP-4), as well as other BMPs. During embryogenesis Noggin is produced by the dorsal mesoderm and is important for the correct bone morphology and neural tissue formation. Mutations in the Noggin-coding gene (NOG) are associated with several bone diseases. The sequence of Noggin protein shows high homology across several species. |
