Mouse IL-12 (25 µg, HEK)
货号：
130-096-708 基本售价：
询价 规格：
25 μg
产品信息
概述| 货号 | 130-096-708 |
| 描述 | IL-12 stands for interleukin 12. Mouse IL-12 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. |
性能| 供应商 | Miltenyi |
| 背景 | Interleukin 12 (IL-12) is a heterodimeric proinflammatory cytokine and a modulator of cell-mediated immunity, which is mainly produced by macrophages, dendritic cells, and B cells. IL-12 stimulates the production and secretion of several cytokines, in particular IFN-γ, by NK cells and T cells, induces proliferation, and enhances the cytotoxic activity within these cell populations. Another important activity of IL-12, acting together with IFN-γ and IL-2, is to drive T helper cell responses toward the TH1 rather than the TH2 phenotype. Moreover, IL-12 is also important in resistance to viral disease and has significant antitumor activity. It has been shown that single chain fusion proteins of naturally occurring heterodimeric cytokines such as IL-12 or IL-23 are bioactive in vitroandin vivo.2,3 |
