Human IL-10 (10 µg)
货号：
130-093-948 基本售价：
询价 规格：
10 μg
产品信息
概述| 货号 | 130-093-948 |
| 描述 | IL-10 stands for interleukin 10. Human IL-10 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. |
性能| 供应商 | Miltenyi |
| 背景 | Interleukin 10 (IL-10) is a α-helical homodimeric cytokine with immunosuppressive and anti-inflammatory properties. It inhibits the secretion of Tʜ1 cytokines such as IL-1, IFN-γ, and TNFα, and the surface expression of molecules for antigen presentation. On the other hand, IL-10 promotes the humoral response, through stimulation of the Tʜ2 response, B cell maturation, and antibody secretion. After secretion, IL-10 binds the receptor IL-10 Rα/IL-10 R1 on target cells. IL-10 is mainly secreted by monocytes, Tʜ2 lymphocytes, regulatory T cells, some B cell subsets, dendritic cells, macrophages, natural killer cells, eosinophils, neutrophils, and mastocytes, but also keratinocytes and hepatic stellate cells. |
