Human IL-4, premium gr. (10 µg)
货号：
130-093-920 基本售价：
询价 规格：
10 μg
产品信息
概述| 货号 | 130-093-920 |
| 描述 | IL-4 stands for Interleukin 4. Human IL-4 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. |
性能| 供应商 | Miltenyi |
| 背景 | Interleukin 4 (IL-4) is a pleiotropic cytokine and plays a central role in humoral and adaptive immune responses. IL-4 is predominantly secreted by activated CD4+ memory and effector TH2 cells, basophils, and mast cells. It promotes the proliferation and differentiation of B cells, as well as immunoglobulin isotype switching, and MHC class II antigen and low-affinity IgE receptor expression. Furthermore, IL-4 induces the differentiation of naive CD4+ T cells into helper TH2 cells, while suppressing TH1 development, and promotes chemotaxis of mast cells and basophils. Excessive IL-4 production and mechanisms involving TH2 types have been associated with immunological disorders, such as IgE-mediated allergy. |
