Human R-Spondin 2, research grade (5 µg)
货号：
130-105-803 基本售价：
询价 规格：
5 μg
产品信息
概述| 货号 | 130-105-803 |
| 描述 | R-Spondin-2 stands for roof plate-specific spondin-2. Human R-Spondin-2 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. |
性能| 供应商 | Miltenyi |
| 背景 | R-Spondin-2, also known as Rspo-2, is a growth factor belonging to the R-Spondin family. R-Spondins are four proteins that support adult stem cell proliferation, and act as Wnt modulators by signaling through the canonical Wnt/β-catenin pathway as agonists. LGR4, LGR5, and LGR6 have been identified as receptors for all four R-Spondins. R-Spondin-2 is expressed in endoderm-derived tissues and is an agonist of Wnt-3a signaling and an inhibitor of DKK-1, Activins, and BMP-4. It plays an important role in morphogenesis of respiratory tract and limbs, and induces cell proliferation of the gastrointestinal tissues. |
