| 货号 | 3775/50 |
| 别名 | (S)-3-(Aminomethyl)-5-methylhexanoi |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Anticonvulsant and antiepileptic; also used to treat neuropathic pain. Binds with high affinity and selectivity to the α2δ subunit of voltage-sensitive Ca2+ channels and modulates their activity. Displays anxiolytic-like activity in ethological and conflict models of anxiety. Analog of GABA (Cat. No. 0344). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 159.23 |
| 分子式 | C8H17NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Kumaret al (2010) Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate. J.Neurochem. 113 552. PMID: 20132471. Arain (2009) Pregabalin in the management of partial epilepsy. Neuropsych.Dis.Treat. 5407. Fieldet al (2001) Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity. Br.J.Pharmacol. 132 1. PMID: 11156553. |