货号 | 3428/10 |
别名 | N,N-Dimethyl-1H-indole-3-ethanamine |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Endogenousσ1 receptor ligand and psychoactive plant compound (Ki = 14.8 μM). Binding to σ1 inhibits voltage-gated Na+ channels and is responsible for the behavioral effects of DMT. Also a 5-HT2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (Ki = 4.0 μM). |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >99 % |
计算分子量 | 188.27 |
分子式 | C12H16N2 |
可溶性/溶解性 | Soluble to 5 mM in ethanol |
参考文献 | Cozziet al (2009) Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transportere and the vesicle monoamine transporter. J.Neural Transm. 116 1591. PMID: 19756361. Fontanillaet al (2009) The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator. Science 323 934. PMID: 19213917. |