货号 | 3131/50 |
别名 | 2-(2-Chlorophenyl)-2-(methylamino)c |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Non-competitive NMDA receptor antagonist (EC50 values are 13.6 and 17.6 μM for NR1/NR2A and NR1/NR2B subunit combinations respectively). Dissociative anesthetic. S-enantiomer (Cat. No. 4379) also available. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 274.19 |
分子式 | C13H16ClNO.HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
参考文献 | Liuet al (2001) Modulation of NMDA receptor function by ketamine and magnesium: part I. Anesth.Pharmacol. 921173. Pallareset al (1995) Effects of ketamine, a noncompetitive NMDA antagonist, on the acquisition of the lever-press response in rats. Physiol.Behav. 57 389. PMID: 7716221. Aniset al (1983) The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br.J.Pharmacol. 79 565. PMID: 6317114. |