| 货号 | 3123/500U |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Selective antagonist of α3β2 nAChR receptors (IC50 values are 9.56 and 252 nM for α3β2 and α7 receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1622.82 |
| 分子式 | C65H95N19O22 |
| 可溶性/溶解性 | Soluble to 5 mg/ml in water |
| 序列号 | GCCSLPPCAANNPDYC (Modifications: Cys-16 = C-terminal amide, Disulfide bridge between 2 - 8, 3 - 16) |
| 参考文献 | Everhartet al (2003) Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors. J.Pharmacol.Exp.Ther. 306 664. PMID: 12734390. Luoet al (1999) Single-residue alteration in α-conotoxin PnIA switches its nAChR subtype selectivity. Biochemistry 38 14542. PMID: 10545176. Fainzilberet al (1994) New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 33 9523. PMID: 8068627. |