| 货号 | 3121/500U |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM for rat α6/α3β2β3 and α3β2 receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1981.3 |
| 分子式 | C79H125N27O2 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| 序列号 | RDPCCSNPVCTVHNPQIC (Modifications: Cys-18 - C-terminal amide, Disulfide bridge between 4 - 10, 5 - 18) |
| 参考文献 | Azam and McIntosh (2005) Effect of novel α-Conotoxins on nicotine-stimulated [3H]Dopamine release from rat striatal synaptosomes. J.Pharmacol.Exp.Ther. 312 231. PMID: 15316087. Chiet al (2005) Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors. Biochem.Biophys.Res.Comms. 3381990. Dowellet al (2003) α-Conotoxin PIA is selective for α6 subunit-containing nicotinic acetylcholine receptors. J.Neurosci. 23 8445. PMID: 13679412. |