| 货号 | 3120/500U |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Selective antagonist of α3β4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including α2β2,α2β4,α3β2,α4β2,α4β4 and α1β1γδ. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1572.76 |
| 分子式 | C65H89N17O21 |
| 可溶性/溶解性 | Soluble to 5 mg/ml in water |
| 序列号 | GCCSYPPCFATNPDC (Modifications: Cys-15 = C-terminal amide, Disulfide bridge between 2 - 8, 3 - 15) |
| 参考文献 | Parket al (2006) An α3β4 subunit combination acts as a major functional nicotinic acetylcholine receptor in male rat pelvic ganglion neurons. Pflugers Arch. 452 775. PMID: 16715294. Naiet al (2003) Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function. Mol.Pharmacol. 63 311. PMID: 12527802. Luoet al (1998) α-Conotoxin AuIB selectively blocks α3β4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release. J.Neurosci. 18 8571. PMID: 9786965. |