| 货号 | 2695/10 |
| 别名 | (S)-N-Ethyl-α-methyl-3-(trifluoromet |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 267.72 |
| 分子式 | C12H16F3N.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Bushet al (2006) Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese mice. Endocrine 29 375. PMID: 16785615. Higginset al (2001) Influence of the 5-HT2C receptor antagonist SB242,084 on behaviour produced by the 5-HT2 agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramine. Br.J.Pharmacol. 133 459. PMID: 11399662. Cacciaet al (1997) Neuropharmacological effects of low and high doses of repeated oral dexfenfluramine in rats: a comparison with fluoxetine. Pharmacol.Biochem.Behav. 57 851. PMID: 9259015. |