货号 | 2557/10 |
别名 | 1-(1-Phenylcyclohexyl)piperidine hydrochloride; PCP |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 279.85 |
分子式 | C17H25N.HCl |
可溶性/溶解性 | Soluble to 40 mM in water |
参考文献 | Jinet al (1997) The involvement of σ receptors in the choice reaction performance deficits induced by phencyclidine. Eur.J.Pharmacol. 319 147. PMID: 9042584. Sharp (1997) Phencyclidine (PCP) acts at σ sites to induce c-fos gene expression. Brain Res. 758 51. PMID: 9203533. Linderset al (1993) Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrochloride: a new potent and selective electrophilic affinity ligand for the NMDA receptor-coupled phencyclidine binding site. J.Med.Chem. 36 2499. PMID: 8355251. |