| 货号 | 1811/10 |
| 别名 | 2-[(Diphenylmethyl)sulfinyl]acetami |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease. Promotes vigilence and wakefulness without the central and peripheral side effects associated with conventional dopaminergic psychostimulants. Mechanism of action is not fully understood, possibly via modulation of catecholamine/GABAergic neurotransmission. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 273.35 |
| 分子式 | C15H15NO2S |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Madraset al (2006) Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro. J.Pharmacol.Exp.Ther. 319 561. PMID: 16885432. Jenneret al (2000) Antiparkinsonian and neuroprotective effects of modafinil in the mtpt-treated common marmoset. Exp.Brain Res. 133 178. PMID: 10968218. Ferraroet al (1997) Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers. Biol.Psychiatry 42 1181. PMID: 9426889. |