| 货号 | 3975/50 |
| 别名 | (3S,11E)-3,4,5,6,9,10-Hexahydro-14, |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Mycotoxin produced by several species of Fusarium fungi. Binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and stimulates the transcriptional activity of both subtypes at concentrations between 1 - 10 nM. Also stimulates growth of T47D breast cancer cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 318.36 |
| 分子式 | C18H22O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Khosrokhavaret al (2009) Effects of zearalenone and α-Zearalenol in comparison with Raloxifene on T47D cells. Toxicol.Mech.Methods 19 246. PMID: 19730705. Takemuraet al (2007) Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro. J.Steroid Biochem.Molec.Biol. 103170. Kuiperet al (1998) Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology 139 4252. PMID: 9751507. |